Dissolution of Common Medications as Modeled by Drug Release Kinetics

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The rate of dissolution for a specific drug is determined by its release kinetics and diffusion coefficient. This Demonstration considers three drugs in everyday use, modeled by a tablet dissolving in a beaker of water. This provides an indication of the pharmacological response to a drug in systemic circulation.

Contributed by: Megan Mitchell and John Yoon (January 2018)
Open content licensed under CC BY-NC-SA


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Reference

[1] S. M. Upadrashta, B. O. Häglund and L.-O. Sundelöf, "Diffusion and Concentration Profiles of Drugs in Gels," Journal of Pharmaceutical Sciences, 82(11), 1993 pp. 1094–1098. doi:10.1002/jps.2600821106.



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