The heart wall is composed of three layers: the epicardium, myocardium and endocardium. This Demonstration shows transmembrane potentials and gating variables during a heartbeat for cardiac cells located in each of these layers. All time values are measured in milliseconds (ms).
We consider the minimal model proposed in  to reproduce experimentally measured characteristics of human ventricular action potential.
 A. Bueno-Orovio, E. M. Cherry and F. H. Fenton, "Minimal Model for Human Ventricular Action Potentials in Tissue," Journal of Theoretical Biology, 253(3), 2008 pp. 544–560. doi:10.1016/j.jtbi.2008.03.029.
Wolfram Demonstrations Project
Published: January 16 2018