Substitution systems whose rules depend on the color of a single element and on the color of the next neighbor produce an unbalanced rate of growth and disappearance. If the rate of disappearances is too large, then almost any pattern will quickly die out, and if there are too few disappearances, then most patterns will grow exponentially or sub-exponentially. This model is a derivation of the neighbor-dependent model, allowing growth from one single cell. You can explore 117649 rules of this kind.