Synergistic Enzyme Hydrolysis of Cellulose in Biomass

The differential equations used in this Demonstration are taken from the paper by K. L. Kadam, E. C. Rydholm, and J. D. McMillan, "Development and Validation of a Kinetic Model for Enzymatic Saccharification of Lignocellulosic Biomass", Biotechnology Progress, 20, 2004 pp. 698–705. Their model combines the synergistic action of endo and exo glucanases into a single lumped enzyme hydrolyzing cellulosic biomass in two reaction steps. Also, these equations ignore any thermal degradation of these enzymes at higher temperatures and hence are more accurate in predicting hydrolysis at lower temperatures.