Dynamic Behavior of a Bioreactor

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The dynamic behavior of a chemostat can be described with the following system of ordinary differential equations:

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where is the dilution rate in , is the biomass concentration in g/l, is the substrate concentration in g/l, is the feed substrate concentration, is the yield, and is the specific growth rate given by the Monod function: , where is the half saturation constant and is the maximum value of the specific growth rate (=1 here).

This Demonstration lets you plot the substrate and biomass concentrations versus time and observe the washout (a phenomenon that occurs when the dilution rate, , is so large that all micro-organisms will end up exiting the bioreactor). Another snapshot shows a situation where the biomass in the reactor reaches a steady-state value different from zero.

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Contributed by: Housam Binous (March 2011)
Open content licensed under CC BY-NC-SA


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